CLL may not need to be treated immediately, but rather monitored for any problems and changes, at which point the need for treatment may be reassessed. Common treatment options include:. Chronic myeloid leukemia CML , also known as chronic myelogenous leukemia, begins in the blood-forming cells of the bone marrow and then, over time, spreads to the blood. Eventually, the disease spreads to other areas of the body.
CML is slow-growing, but once it starts causing symptoms, these may include fatigue, fever, weight loss and an enlarged spleen. Around half of CML cases are diagnosed by a blood test before symptoms have begun. Among the many different types of leukemia, some are less common than others. Three rarer leukemia types—prolymphocytic leukemia PLL , large granular lymphocyte leukemia LGL and hairy cell leukemia HCL —share some of the same characteristics as lymphocytic leukemias and are sometimes considered subtypes of chronic or acute lymphocytic leukemia CLL and ALL.
Myelodysplastic syndromes are conditions related to leukemia that are also rare. If it causes symptoms, they may be similar to other types of leukemia flu-like symptoms, easy bruising, unexplained weight loss.
Diagnosis may include blood tests as well as bone marrow aspiration and biopsy. However, relapse is common. Large granular lymphocytic LGL leukemia is a chronic type of leukemia that causes the body to produce abnormally large lymphocytes. By the time patients are diagnosed with this condition, symptoms tend to be present and include flu-like symptoms, frequent infections and unexplained weight loss.
People with autoimmune diseases tend to be more at risk for developing LGL. Diagnosis may include blood tests and bone marrow aspiration and biopsy. Most patients require treatment shortly after diagnosis, which may include drugs that suppress the immune system.
Others may be able to hold off on treatment to see whether problems arise. HCL is caused when bone marrow makes too many B cells lymphocytes , a type of white blood cell that fights infection. As the number of leukemia cells increases, fewer healthy white blood cells, red blood cells and platelets are produced. Under a microscope, HCL cells appear to have thin, hair-like outgrowths. Symptoms of HCL may be similar to other types of leukemia and resemble the flu. Bone marrow aspiration and biopsy and blood tests are the primary diagnostic tools.
When complications related to HCL do occur—such as low blood cell counts, frequent infections or lymph node swelling—chemotherapy is typically used. Typically, lymphoproliferative disorders are seen after transplantation whether of bone marrow stem cells or solid organs such as a kidney or liver , where chronic immune suppression treatment is used to prevent the transplanted tissues from harming the body or vice versa.
That process has now given rise to the lymphoproliferative disease. While treatment of the underlying CLL might be sufficient for managing the lymphoproliferative disorder, directly treatment of the lymphoproliferative disorder might also be effective. Some biological therapies may actually treat both conditions. Talking with your oncologist to figure out the exact nature of the lymphoproliferative disorder is the first step toward understanding how best to proceed with treatment.
I have just been diagnosed with CLL. It was discovered in a blood test related to my annual physical. I am in the very early, early stage of this disease. We will just monitor my blood work periodically. Can I still exercise? Can I snow ski? Can I drink alcohol? I really have not been told anything. I just don't want to do anything that might speed up the progress of this disease.
Continue to exercise, work and play as before. There are some good online resources, including this site, of safe things to do and in particular, bad things to do. By subscribing you agree to the Terms of Use and Privacy Policy. Health Topics. Health Tools. There are 2 main groups of leukaemia - acute and chronic leukaemia. They are then grouped by the type of white blood cell that is affected. Whether a leukaemia is acute or chronic describes how quickly the leukaemia is likely to develop and get worse.
Acute leukaemias tend to develop quickly and get rapidly worse if they are not treated. Chronic leukaemias develop slowly and tend to get worse slowly, over a long time. In chronic leukaemia, the white blood cells are almost fully developed but are not completely normal. They still work, but not as well as they should do at fighting infection.
Your body makes too many of these abnormal white blood cells. The difference between them is the type of white blood cell that has become cancerous. In CLL, the abnormal cells develop from early blood cells called the lymphoid blood stem cells. The cancerous white blood cells are B lymphocytes, also called B cells. In CML, the abnormal leukaemia cells develop from early blood cells called the myeloid blood stem cells.
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